Biochip – based test systems are a simple and state-of-the-art tool for instant differential cancer diagnosis, target search for therapeutic purposes and evaluation of the disease prognosis
Biochip-based test systems for immunocytochemical analysis are a simple and state-of-the-art tool for instant differential diagnosis of malignant tumours in a human body, as well as target search for drug treatment.
Their advantages include great accuracy of obtained results (no less than 96%), minimum analysis time (60 minutes), the fact that no morphologist is required in the staff structure of a medical institution, the possibility of remote consultation in terms of the analysis results with the participation of an experienced specialist, and a low cost for the end user.
Biochips used in clinical practice enable you: |
To make histogenetic diagnosis of tumours |
To define the nosological variant of a growth |
To detect the primary tumour by metastasis with an unknown primary site |
To predict tumour development |
To recognise a malignant transformation of cells |
To form the basis for targeted therapy |
To evaluate the resistance or sensitivity of tumour cells to chemotherapeutic and target compounds |
The diagnosis process with the help of a biochip is based on the principle of direct fluorescent immunocytochemistry with subsequent morphological analysis.
We presently offer 7 types of test systems:
«ЕРН» Biochip – For determining the immunophenotype of breast cancer cells;
List of markers |
Рецепторы эстрогена (РЭ) |
Рецепторы прогестерона (РGR) |
Her2-neu (EGFR 2) |
EGFR |
Ki67 |
«SER» Biochip – determining the nature of the serous fluid;
List of markers | |
СА-125 | |
РЭА | |
Цитокератин 7 (СК7) | |
Цитокератин 20 (СК 20) | |
РЭ (ER) | |
TTF | |
WT-1 | |
BerEp4 | |
Виментин (VIM) |
«TYR» Biochip – for differential diagnosis of thyroid neoplasms ;
List of markers | |
Тиреоглобулин (TG) | |
Кальцитонин (CT) | |
TTF1 | |
Галектин 3 (GAL 3) | |
Мезотелиальный антиген НВМЕ1 | |
Цитокератин 19 (СК19) | |
CD44v6 (HCAM) | |
p53 |
«Pulmo» Biochip – For diagnosing lung cancer;
List of markers | |
СК7 | |
СК 20 | |
TTF1 | |
Хромогранин А | |
Cинаптофизин | |
p53 | |
CD 56 | |
СК5/6 | |
р63 |
«PNV» Biochip – For diagnosing malignant tumours in the genitourinary tract;
List of markers | |
р16 (CDKN2A) | |
Ki67 | |
р63 | |
Цитокератины 5/6 (СК5/6) | |
CK7 | |
CK 20 | |
СА125 | |
WT1 | |
Уроплакин (UPK3А) | |
FAS (CD95) | |
CDX2 |
«NOD1» Biochip – To search for an undetected primary site;
List of markers | |
РЭ (ER) | |
СК7 | |
СК20 | |
ПСА (PSA) | |
Кальретинин (СR) | |
Хромогранин А | |
CD56 (NCAM) | |
CD10 (NEP) | |
CD44 (HCAM) | |
CK19 | |
RCC | |
TTF1 | |
ЭМА | |
Тиреоглобулин (TG) | |
CDX2 |
«NOD2» Biochip – To search for an undetected primary site.
List of markers | |
СК7 | |
СК20 | |
CD138 (SDC1) | |
Виментин (VIM) | |
ЕрСam | |
CD99 | |
S100 | |
Десмин | |
ЭМА | |
Мелан А (MLANA) | |
НМВ 45 (ME20M) | |
РЭА | |
HBME1 | |
Остеонектин (ОN) | |
Остеокальцин (OC) |
A standard biochip has compartments covered with a protective film. These compartments contain fluorescent-labelled proteins.
