Biochip – based test systems are a simple and state-of-the-art tool for instant differential cancer diagnosis, target search for therapeutic purposes and evaluation of the disease prognosis
Biochip-based test systems for immunocytochemical analysis are a simple and state-of-the-art tool for instant differential diagnosis of malignant tumours in a human body, as well as target search for drug treatment.
Their advantages include great accuracy of obtained results (no less than 96%), minimum analysis time (60 minutes), the fact that no morphologist is required in the staff structure of a medical institution, the possibility of remote consultation in terms of the analysis results with the participation of an experienced specialist, and a low cost for the end user.
| Biochips used in clinical practice enable you: |
| To make histogenetic diagnosis of tumours |
| To define the nosological variant of a growth |
| To detect the primary tumour by metastasis with an unknown primary site |
| To predict tumour development |
| To recognise a malignant transformation of cells |
| To form the basis for targeted therapy |
| To evaluate the resistance or sensitivity of tumour cells to chemotherapeutic and target compounds |
The diagnosis process with the help of a biochip is based on the principle of direct fluorescent immunocytochemistry with subsequent morphological analysis.
We presently offer 7 types of test systems:
«ЕРН» Biochip – For determining the immunophenotype of breast cancer cells;
| List of markers |
| Рецепторы эстрогена (РЭ) |
| Рецепторы прогестерона (РGR) |
| Her2-neu (EGFR 2) |
| EGFR |
| Ki67 |
«SER» Biochip – determining the nature of the serous fluid;
| List of markers | |
| СА-125 | |
| РЭА | |
| Цитокератин 7 (СК7) | |
| Цитокератин 20 (СК 20) | |
| РЭ (ER) | |
| TTF | |
| WT-1 | |
| BerEp4 | |
| Виментин (VIM) | |
«TYR» Biochip – for differential diagnosis of thyroid neoplasms ;
| List of markers | |
| Тиреоглобулин (TG) | |
| Кальцитонин (CT) | |
| TTF1 | |
| Галектин 3 (GAL 3) | |
| Мезотелиальный антиген НВМЕ1 | |
| Цитокератин 19 (СК19) | |
| CD44v6 (HCAM) | |
| p53 | |
«Pulmo» Biochip – For diagnosing lung cancer;
| List of markers | |
| СК7 | |
| СК 20 | |
| TTF1 | |
| Хромогранин А | |
| Cинаптофизин | |
| p53 | |
| CD 56 | |
| СК5/6 | |
| р63 | |
«PNV» Biochip – For diagnosing malignant tumours in the genitourinary tract;
| List of markers | |
| р16 (CDKN2A) | |
| Ki67 | |
| р63 | |
| Цитокератины 5/6 (СК5/6) | |
| CK7 | |
| CK 20 | |
| СА125 | |
| WT1 | |
| Уроплакин (UPK3А) | |
| FAS (CD95) | |
| CDX2 | |
«NOD1» Biochip – To search for an undetected primary site;
| List of markers | |
| РЭ (ER) | |
| СК7 | |
| СК20 | |
| ПСА (PSA) | |
| Кальретинин (СR) | |
| Хромогранин А | |
| CD56 (NCAM) | |
| CD10 (NEP) | |
| CD44 (HCAM) | |
| CK19 | |
| RCC | |
| TTF1 | |
| ЭМА | |
| Тиреоглобулин (TG) | |
| CDX2 | |
«NOD2» Biochip – To search for an undetected primary site.
| List of markers | |
| СК7 | |
| СК20 | |
| CD138 (SDC1) | |
| Виментин (VIM) | |
| ЕрСam | |
| CD99 | |
| S100 | |
| Десмин | |
| ЭМА | |
| Мелан А (MLANA) | |
| НМВ 45 (ME20M) | |
| РЭА | |
| HBME1 | |
| Остеонектин (ОN) | |
| Остеокальцин (OC) | |
A standard biochip has compartments covered with a protective film. These compartments contain fluorescent-labelled proteins.
